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Seed Grants 2005
Up one levelIn 2005, the Alliance for NanoHealth posted a request for collaborative research proposals that investigated innovative biomedical nanotechnology projects. Over 60 pre-proposals were received, 34 teams were invited to submit a full-proposal, and 10 seed grant awards were granted.
The Alliance for NanoHealth allocated approximately $2.0M to fund 10 externally reviewed seed grant projects in 2005. The ANH Community responded with vigor: 91 investigators self-assembled to form 34 nanotechnology-based research projects, 16+ distinct nanotechnologies were showcased, and 6 institutions in all participated.
Although the funding has recently been released to the 10 teams of investigators (October 2006), the scientific/clinical impact is already becoming evident. The Alliance is proud to hear that at least 1 of the 10 seed grant recipients has already received additional RO1 funding as the result of the collaborative efforts inspired by the Alliance's seed grant opportunity. The ANH is confident that future success stories will be soon to follow.
- Nanorods-mediated gene therapy in bladder cancer
- Principal Investigator: Liana Adam, MD, PhD (UTMDACC) Co-Principal Investigator: Jason Hafner, PhD (Rice)
- Self-Assembling Peptide-Amphiphile Nanofibers as a Scaffold for Dental Stem Cells
- Principal Investigator: Jeffrey D. Hartgerink, Ph.D. (Rice), Co-Investigator: Rena D'Souza, D.D.S., Ph.D. (UTHSC-H)
- Bimodally-Targeted, Magnetically-Responsive Nanoparticles as Drug Carriers
- Principal Investigator: Jim Klostergaard , Ph.D. (UTMDACC), Co-Investigator's: Waldemar Priebe, Ph.D. (UTMDACC), Joan Bull, M.D. (UTHSC-H), David Gorenstein, Ph.D. (UTMB/APTAMED), Charles Seeney, M.S. (NANOBIOMAGNETICS, INC.)
- Feasibility of selective laser elimination of leukemia cells targeted with gold and silver nanorods.
- Principal Investigator: Marina Konopleva, M.D., Ph.D. (UTMDACC); Co-Investigator's: Bahman Anvari, Ph.D. (Rice), Alexander Oraevsky, Ph.D. (Fairway Medical Technologies, Inc.)
- On-command control of blood pool residence time for nanoparticle-based molecular imaging
- Principal Investigator: Vikas Kundra,M.D., Ph.D. (UTMDACC), Co-Investigator: Ananth Annapragada, Ph.D. (UTHSC-H)
- Nanomagnetic Biosensor Array for Few-Cell Cancer Diagnostics
- Principal lnvestigator: Dmitri Litvinov, Ph.D (UH); Co-Investigator's: Richard Willson, Ph.D. (UH), John C. Wolfe, Ph.D. (UH), Mini Kapoor, Ph.D. (UTMDACC)
- Guided Microvascular Formation and Cellular Infiltration for Tissue Regeneration Applications in Nano-Structured Silk Fibroin-Chitosan Scaffolds
- Principal Investigator: Anshu B. Mathur, Ph.D. (UTMDACC); Co-Investigator's: Rebecca Richards-Kortum, Ph.D. (Rice), Peter C. Gascoyne, Ph.D. (UTMDACC), Gregory P. Reece, M.D. (UTMDACC)
- Nano-Therapeutics to Enhance Wound Healing
- Principal Investigator: Joan E. Nichols, Ph.D. (UTMB); Co-Investigator: Joaquin Cortiella, M.D. M.P.H (UTMB), Nicholas A. Kotov, Ph.D. (University of Michigan), Rigoberto C. Advincula, Ph.D. (UH)
- Modulation of Inner Ear Nanomechanics
- Principal Investigator: John S. Oghalai, M.D. (BCM); Co-Investigator: Bahman Anvari, PhD. (Rice)
- Development of asymmetric liposomal nanoparticles for targeted delivery of siRNA to silence cyclin D1 expression and tumor regression in hepatocellular carcinoma
- Principal Investigator: Sundararajah Thevananther, PhD. (BCM); Co-Investigator's: Kishore K. Mohanty, Ph.D. (UH), Cumaraswamy Vipulanandan, Ph.D. (UH)